Feb 2024 Third United States patent granted for our nasal drug delivery technology.

Sep 2023 Japanese patent granted for our nasal drug delivery technology.

Mar 2023 Canadian patent granted for our nasal drug delivery technology.

Jul 2021 Rivamist® nasal spray human factors and engineering studies successfully completed.

Feb 2021 Second United States patent granted for our nasal drug delivery technology.

Oct 2020 Australian patent granted for our nasal drug delivery technology.

Aug 2020 European patent granted for our nasal drug delivery technology.

Jul 2020 Pharmacokinetic bridge study of Rivamist® nasal spray and Exelon® oral capsule successfully completed.

• Nasal delivers twice the rivastigmine exposure as oral at an equivalent 3 mg dose
• Rivastigmine plasma concentration shown for nasal 4 mg and oral 3 mg (below)

AusIndustry funding support acknowledged, ​​ACTRN12619001513101, Mean ± SD, n= 16, ​Scientific title: A randomised, crossover, two period, pharmacokinetic, bioavailability and safety study of a single dose of the novel rivastigmine nasal spray and single dose rivastigmine (Exelon, registered trademark) oral capsule in young healthy adult males. Exelon is a registered trademark of Novartis Corp.

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Sep 2019   AusIndustry AC grant to support the development of our proprietary rivastigmine nasal spray for Alzheimer's and Parkinson's disease dementia.

Aug 2019   United States patent granted for our nasal drug delivery technology.

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Journal Publication

• Morgan TM, Soh B. Absolute Bioavailability and Safety of a Novel Rivastigmine Nasal Spray in Healthy Elderly Individuals. Br J Clin Pharmacol. 2017 83(3):510-516   PMID: 27639640   DOI: 10.1111/bcp.13133​

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Conference Posters

• Morgan TM. Deconvolution of Nasal Absorption of Rivastigmine in Humans and Future Clinical Development. J Prev Alz Dis 2016. 3(4):353; P2-39.
• Morgan TM. Absolute bioavailability and safety of a novel rivastigmine intranasal spray in healthy elderly individuals. J Prev Alz Dis 2015. 2(4):269-396; P2-55.